Aaron Carroll, Congratulations on the Promotion. But Did Get a Demotion?
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Before 2000, 57% of trials showed “significant benefit” but after changes in transparency, only 8% did.

"...A 2015 study published in PLOS ONE followed how many null results were found in trials funded by the National Heart, Lung and Blood Institute before and after researchers were required to register their protocols at a public website. This rule was introduced in 2000 in part because of a general sense that researchers were subtly altering their work — after it was begun — to achieve positive results. In the 30 years before 2000, 57 percent of trials published showed a “significant benefit.” Afterward, only 8 percent did...."
Aaron Carroll, Congratulations on the Promotion. But Did Science Get a Demotion?"New York Times, December 31, 2018, https://www.nytimes.com/2018/12/31/upshot/congratulations-on-the-promotion-but-did-science-get-a-demotion.html























