Edward Conard

Top Ten New York Times Bestselling Author

  • “…a fresh argument for the productive value of inequality.” - David Autor, Professor of Economics, Massachusetts Institute of Technology
Upside of Inequality Unintended Consequences Oxford
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Edward Conard

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Preponderance of Significant Results Fell From 57% to 8% of Experiments When Protocols Preregistered

Another worrisome story in the New York Times reports “…A 2015 study published in PLOS ONE followed how many null results were found in trials funded by the National Heart, Lung and Blood Institute before and after researchers were required to register their protocols at a public website. This rule was introduced in 2000 in part because of a general sense that researchers were subtly altering their work — after it was begun — to achieve positive results. In the 30 years before 2000, 57 percent of trials published showed a ‘significant benefit.’ Afterward, only 8 percent did….” These findings parallel many other studies here, here, and here, for example, and also here, here,  here and here. I raised similar concerns about the statistical integrity of supposedly unbiased academic studies in my last book, The Upside of Inequality (pages 224-225).

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